Resistant non-Hodgkin's lymphomas or those presenting with poor prognostic features following an initial response.Acute leukemia in remission in patients who have a high probability of relapse and who have no human leucocyte antigens (HLA)-matched donor.The NCD lists the following nationally covered indications: Hematopoietic Progenitor Cell (HPC) Autologous Transplantation This Medical policy article describes additional locally covered indications for stem cell transplant. The CMS National Coverage Determination (NCD) for Stem Cell Transplantation describes nationally covered indications for stem cell transplant, the details of which will not be repeated here. (CMS Publication 100-03, Medicare National Coverage Determinations(NCD) Manual, Chapter 1, Part 2: Section 110.23). When bone marrow or peripheral blood stem cell transplantation is non-covered, none of the steps are covered. When bone marrow or peripheral blood stem cell transplantation is covered, all necessary steps are included in coverage. bone marrow and peripheral blood stem cell transplantation is a process which includes mobilization, harvesting, and transplant of bone marrow or peripheral blood stem cells and the administration of high dose chemotherapy or radiotherapy prior to the actual transplant. (CMS Publication 100-03, Medicare National Coverage Determinations (NCD) Manual, Chapter 1, Part 2: Section 110.23). A hematopoietic stem cell is a cell isolated from blood or bone marrow that can renew itself, differentiate to a variety of specialized cells, can mobilize out of the bone marrow into circulating blood, and can undergo programmed cell death, called apoptosis - a process by which cells that are unneeded or detrimental self destruct. Hematopoietic stem cells are multi-potent stem cells that give rise to all the blood cell types these stem cells form blood and immune cells.
Allogeneic HSCT may also be used to restore function in recipients having an inherited or acquired deficiency or defect. Allogeneic stem cell transplantation (HSCT) is a procedure in which a portion of a healthy donor's stem cell or bone marrow is obtained and prepared for intravenous infusion. (AuSCT) must be used to effect hematopoietic reconstitution following severely myelotoxic doses of chemotherapy (HDCT) and/or radiotherapy used to treat various malignancies. (AuSCT) is a technique for restoring stem cells using the patient's own previously stored cells. Stem cell transplantation is a process in which stem cells are harvested from either a patient's (autologous) or donor's allogenic bone marrow or peripheral blood for intravenous infusion. Not endorsed by the AHA or any of its affiliates. Presented in the material do not necessarily represent the views of the AHA. Preparation of this material, or the analysis of information provided in the material. The American Hospital Association (the "AHA") has not reviewed, and is not responsible for, the completeness orĪccuracy of any information contained in this material, nor was the AHA or any of its affiliates, involved in the
AUTOLOGOUS STEM CELL TRANSPLANT ICD 10 MANUAL
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